Goalkeeper Andre Onana will return to Manchester United to discover the extent of an injury suffered playing for Cameroon in a World Cup qualifier.
Onana, 27, was substituted in the 81st minute of Friday's 3-0 victory over Mauritius in Douala, having been injured making a save.
The goalkeeper has pulled out of Cameroon's squad for Tuesday's match against Libya.
Cameroon officials did not give details of the type or severity of the injury.
Though the 27-year-old will miss the clash with Libya, it remains to be seen if he will be available for United's clash with Everton next Sunday. United will resume their Premier League campaign after the international break with a relatively short trip to Goodison Park.
If the Cameroonian is deemed unfit, it is almost certain that fellow summer signing Altay Bayindir will be awarded his debut for the club. The 25-year-old, who joined United from Fenerbahce, started Turkey's 3-2 win over Germany in an international friendly on Saturday evening.
United manager Erik ten Hag is already facing a number of injury issues as his squad prepare to return from the international break with a Premier League with a Premier League trip to Everton on 26 November and a Champions League visit to Galatasaray three days later.
Lisandro Martinez (foot), Casemiro (thigh) and Christian Eriksen (knee) are all definitely out while Luke Shaw (muscle problem), Jonny Evans (thigh), Tyrell Malacia (knee), Aaron Wan-Bissaka (illness) and Rasmus Hojlund (thigh) are facing a race to be fit in time.
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