The Catalan outfit will enter the cup contest off the back of a 4-1 defeat to Real Madrid in the final of the Spanish Super Cup on Sunday evening, and there is pressure on head coach Xavi to guide the team into the next round of this particular competition.
Barcelona are without the services of Joao Cancelo, Gavi, Marc-Andre ter Stegen, Inigo Martinez, Marcos Alonso and Raphinha due to injury problems.
Meanwhile, key central defender Ronald Araujo, who is currently being heavily linked with a move away from the club, is suspended for this match alongside Lamine Yamal.
Recent arrival Vitor Roque was surprisingly not involved against either Osasuna or Real Madrid in the Spanish Super Cup, but he is in the squad for this game and will receive some minutes.
Marc Guiu, Hector Fort, Marc Casado, Pau Victor, Pau Cubarsi and Diego Kochen are also given opportunities to due to the first-team absences at Barcelona.
Unionistas play their football in Spain's third tier, and it would therefore be a huge shock if the home side were able to navigate their way into the next stage.
However, Barcelona had a scare in the last round of the competition against fourth-tier outfit Barbastro, only running out 3-2 winners to advance to the last-16.
The Catalan outfit will be aiming to return to winning ways on Thursday before switching their attention back to La Liga, facing a trip to Seville to tackle Real Betis on Sunday.
«We have to change our mindset. After the defeat in the Super Cup, we must have a good feeling. We are the favourites,» Barcelona boss
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