Jurgen Klopp out to achieve Liverpool first in final Merseyside derby
The midweek encounter will represent Klopp's final Merseyside derby as Liverpool manager, as the German confirmed in January that he would step down from his job at the end of the season.
Depending on Arsenal's result against Chelsea on Tuesday night, the second-placed Reds could be three points behind the league-leading Gunners by the time they take to the field 24 hours later.
Reigning champions Manchester City are also hot on Liverpool's heels, sitting just one point worse off with a game in hand, but the Reds prevailed 2-0 in their most recent Merseyside derby with Everton in October.
That triumph represented Klopp's ninth from 16 Merseyside derbies in the Premier League, and he could now become the first Liverpool coach to oversee 10 victories against the Reds' bitter adversaries in the competition.
Klopp out to emulate Sir Kenny Dalglish Merseyside derby recordLiverpool have only been beaten once by Everton in all tournaments since Klopp took charge in October 2015, and his first Merseyside derby towards the end of the 15-16 season ended in a 4-0 Anfield success.
As a result, the former Borussia Dortmund manager could also emulate Sir Kenny Dalglish as just the second Liverpool boss to win both their first and last Merseyside derbies in the league.
Dalglish's maiden and final victories in this matchup came 27 years apart, as he masterminded a 3-2 success in September 1985 during the days of the First Division, before a Steven Gerrard hat-trick saw the Reds triumph 3-0 in 2012.
It is not just managerial landmarks that could be hit in the 244th
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