The 30-year-old has been managing the problem since March and was forced to undergo surgery, although she recovered in time to represent England at this summer's World Cup.
Since the resumption of domestic football, Bright has continued to feature regularly in the heart of the Blues' backline, starting each of their first six Women's Super League fixtures and their opening Champions League group-stage clash with Real Madrid on November 15.
However, the defender was then absent for the 5-1 thrashing of Liverpool last weekend, before also being forced to sit out the Blues' 4-1 Champions League success over Paris FC on Thursday night.
Speaking to the media ahead of the continental clash, Chelsea boss Emma Hayes admitted that Bright's load needed to be carefully managed, as she had rushed herself back to be ready for the World Cup.
«Having so many games in quick succession, we are managing her load. We wanted to give her a little bit of extra time, but she is very much in doubt for tomorrow,» Hayes told the media.
«Prior to the World Cup, she had surgery on her knee, so her preparation going into the World Cup wasn't ideal. She rushed herself back from the World Cup and into the Chelsea season. Perhaps she needed a little bit longer.
»Her knee is a little big angry at the minute. It's nothing too detrimental, but we are listening to her body and how she is feeling. We are taking it on a day-to-day basis."
Hayes's comments poured doubt on Bright's availability for the Nations League, and England have now confirmed that the 30-year-old has pulled out of the squad for their final two
Read on sportsmole.co.uk