Referee Jarred Gillett will wear a camera during the Premier League game between Crystal Palace and Manchester United, live on Sky Sports.
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Gillett will don a head-mounted 'RefCam' at Selhurst Park in a Premier League first.
The technology was approved for use in Monday's game by football's lawmakers, IFAB, as well as Premier League refereeing body, PGMOL, and both clubs.
But the Premier League said that Gillett would only wear the kit as part of filming "for a one-off short programme promoting match officials".
The footage from Gillett's camera will not be broadcast live, but will be shown later in the year as part of a programme "aimed at offering further insight and education into the demands of officiating in the Premier League".
The technology has previously been attached to the referee's chest, but Gillett will wear a head-mounted device that connects to the usual officials' communications system.
Referee Rob Jones wore a camera mounted on his chest during a pre-season game between Chelsea and Brighton in Philadelphia last summer.
During another pre-season Summer Series game, ref Peter Bankes captured a stunning Harry Wilson goal for Fulham.
'RefCam' has also been introduced in Germany's Bundesliga this season, with match official Daniel Schlager wearing a camera during a 2-2 draw between Frankfurt and Wolfsburg in March that saw early goals, bookings and an injury-time equaliser.
A camera was attached to Schlager's headset to film the match from his viewpoint, with a sound link conveying his conversations on the pitch.
In another attempt to provide insight into the referee's experience, Emily Heaslip was mic'd up - for the first time in Sky Sports history - during a WSL match
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