Holders Manchester City will face Chelsea in the FA Cup semi-finals with rivals Manchester United taking on outsiders Coventry.
The draw for the last four raises the prospect of a repeat of last season's all-Manchester final.
Treble-chasing City eased through with a comfortable 2-0 victory over Newcastle on Saturday while Chelsea saw off Leicester 4-2.
United's reward for a thrilling 4-3 extra-time victory over Liverpool on Sunday is a clash with Championship outfit Coventry, who stunned Wolves 3-2 at Molineux.
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