Set to lose Lionel Messi and eight other players to international duty next week, Inter Miami first head west for a cross-country road trip at defending champions LAFC on Sunday.
It's a huge match for the MLS side that was held to a scoreless draw last time out, a frustrating affair against Nashville SC amidst the chase for a playoff spot.
Inter Miami sat bottom of the Eastern Conference at the restart of MLS action following the Leagues Cup, and after collecting four points in two games since, they are still 14th in the table, level on points with the bottom dwellers Toronto FC. They are 10 points adrift of a playoff spot with 10 matches to go.
LAFC, meanwhile, are second in the Western Conference, a good distance back of St. Louis City SC but still in great position to host playoff games if they can keep pace.
Recap the scoreless draw with Nashville SC as Lionel Messi held in check for first time
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This MLS regular season match at BMO Stadium kicks off on Sunday, September 3 at 7 p.m. local time in Los Angeles, California.
Here's how that time translates across some of the major territories:
A full tracker of all players who have swapped shirts with Lionel Messi with Inter Miami
Club talisman Carlos Vela has been rested a few times this season during road games, but here at home he should start alongside Golden Boot candidate Denis Bouanga up front. The same too for veteran defender Giorgio Chiellini, who was left out of the squad for the previous match against Charlotte FC on the road.
In midfield, Kellyn Acosta has come off the bench the last two matches, but he could be brought on to help shore up the middle of the pitch, with Mateusz Bogusz or Timothy Tillman sacrific
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