Wilson was handed his first start of 2024 in the Magpies' 3-2 win at Nottingham Forest last weekend, but he was seen in some discomfort towards the end of the contest and used his shirt to put his arm in a temporary sling.
Howe initially thought that Wilson had sustained a shoulder injury after a battle with a Forest defender, but the 31-year-old has instead pulled a pectoral tendon which requires surgery following a scan.
Wilson is expected to be sidelined for up to 12 weeks and is facing a race against time to return before the end of the season, while his chances of representing England at Euro 2024 are also at risk.
Speaking about Newcastle's No.9 at a press conference on Friday ahead of Saturday's Premier League home clash with Bournemouth, Howe said: «It was a really strange injury, getting in a tussle with the centre-back right at the end of the game. Initially, from my view, I thought he'd hurt his shoulder but it was a muscle in his pec so we had it scanned.
»We hoped he could carry on and he felt good. He was moving his arm at full strength but when he went to see a specialist, it was apparent quite early on that he needed it operated on and he's having that as we speak.
«It's no doubt a big blow to him because I think he's looking at various things. His first priority has always been Newcastle and he feels it has been a stop start season for him. He takes that burden of being one of our two strikers very seriously and he's desperate to do well and score goals.
»He was very disappointed in that perspective and he had England on the horizon as well so
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