The former Leicester City man came off in first-half injury time during Monday's 4-1 loss to Chelsea, having damaged his ankle while sliding on the turf with nobody around him.
Ange Postecoglou was none the wiser about the severity of Maddison's problem after the game, simply stating that the 26-year-old would need further assessment in the coming days.
Nevertheless, Maddison was named in Gareth Southgate's 25-man group for this month's Euro 2024 qualifiers with North Macedonia and Malta, as the Three Lions aim to seal a first-placed finish in Group C.
However, Spurs announced on Friday morning that Maddison has withdrawn from the national team camp and will remain at Hotspur Way to undergo rehabilitation with the club's medical staff.
«We can confirm that James Maddison has been withdrawn from the England squad due to an ankle injury,» Tottenham said on X, formerly known as Twitter.
«The midfielder will not feature in the Three Lions' UEFA EURO 2024 qualifiers against Malta and North Macedonia, and will remain at Hotspur Way for rehabilitation with the Club's medical staff.»
Maddison's England withdrawal also casts further doubt over his availability for Saturday's Premier League clash with Wolverhampton Wanderers, where Postecoglou will be working with a decimated group of players.
The Lilywhites have lost both of Destiny Udogie and Cristian Romero to suspension owing to their dismissals against Chelsea, with the former serving a one-game ban for two yellow card offences.
Meanwhile, Romero will begin a three-match domestic ban for his straight red card, meaning that the
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