Alexander Isak struck eight minutes after the break to seal a 1-0 victory for the Magpies – their first over City in any competition in 11 attempts – in front of a crowd of 51,692 at St James Park.
Guardiola made eight changes, three of them to include Mateo Kovacic, Kalvin Phillips and Jack Grealish, and – while having indicated in advance that the competition was the least of his priorities – saw his side dominate for long periods but ultimately fail to turn the pressure they exerted into goals.
With Phillips and Kovacic controlling the midfield battle, the Magpies were absent as an attacking force for much of the first half.
By contrast the link between Rico Lewis, Oscar Bobb – making his first senior start – and Sergio Gomez down the City right proved profitable repeatedly.
Goalkeeper Nick Pope was called upon for the first time with 18 minutes gone when Bobb turned smartly on Phillips’ ball to feet and raced towards goal before feeding Julian Alvarez, whose low shot was blocked by the keeper’s boot.
Paul Dummett had to make a perfectly-timed challenge to deny Grealish a clear run at goal and Sandro Tonali threw himself into the path of Kovacic’s goal-bound strike with Newcastle’s inability to retain the ball causing them all kinds of problems.
Alvarez blazed a 28th-minute shot across goal after running on to Bobb’s clever flick from Kovacic’s square ball as the home side chased shadows, although they might have changed the narrative of the first half four minutes before the break.
Joelinton’s interception on halfway allowed Isak to feed Jacob Murphy, who surged forward before firing across keeper Stefan Ortega, who blocked with a leg.
Eddie Howe made a double change before the restart, replacing Lewis Hall and 17-year-old
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