Owing to Sunday's goalless draw with reigning champions Manchester City, the Gunners are no longer in control of the title race, and the crown is now Liverpool's to lose with just nine games to go.
However, with the Reds only two points clear at the top and not in action again until Thursday evening, victory for Arsenal over the Hatters would send them to the summit for at least 24 hours.
Mikel Arteta's men already have one victory against Rob Edwards's side under their belts this season, although they were made to work extremely hard for an enthralling 4-3 triumph at Kenilworth Road back in December.
Declan Rice's last-gasp header saw Arsenal came out on top in that seven-goal thriller, and from each of their other four games against promoted sides this season, the Gunners have run out convincing winners.
Gunners on verge of breaking own recordArsenal's two meetings with Sheffield United have seen the North London giants record a staggering 11 goals in 5-0 and 6-0 wins, while they have triumphed 5-0 and 3-1 over Burnley in their two meetings this term.
As such, the Gunners have already scored 23 goals against 2022-23 Championship teams this season, and should they net at least twice on Wednesday, they will set a new all-time high for goals against newly-promoted sides in a single Premier League season.
Arsenal are already the proud owners of such a record, as the 2012-13 team under Arsene Wenger struck 24 times in their six games with Southampton, Reading and West Ham United.
The Gunners therefore only need to score once to equal their own feat on
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