The Irons have been fighting tooth and nail to bring the world's most expensive defender to the London Stadium after he was stripped of the Red Devils captaincy by Erik ten Hag.
West Ham had apparently agreed a £30m deal with Man United for Maguire's signature, but a deal collapsed after the defender failed to agree terms over a payoff with the Red Devils.
Instead, David Moyes's men brought Dinos Mavropanos back to England from Stuttgart for £18m, but they have supposedly been considering reigniting their interest in Maguire in the final week of the transfer window.
West Ham would have apparently been happy to increase their initial £30m bid, allowing Man United to use the funds to negotiate Maguire's payoff, but Raphael Varane's injury has thrown a spanner into the works.
The Frenchman came off injured in the weekend's 3-2 win over Nottingham Forest, and The Mirror claims that he could miss the next six weeks as he recuperates.
As a result, Man United are no longer actively trying to offload Maguire, and a recent report stated that any future approaches from West Ham would be swiftly rebuffed.
Having received little encouragement that a deal could be revived, journalist Florian Plettenberg has said that West Ham have now withdrawn their interest, as any move for the 30-year-old would now be far too expensive.
Maguire would have supposedly been willing to accept a significant salary decrease to play regularly in West Ham colours, but the England international is also willing to stay and fight for his place at Old Trafford.
With Varane potentially missing the whole of September, Victor Lindelof will likely come in
Read on sportsmole.co.uk