The 31-year-old appeared to be in some discomfort towards the end of the Magpies' 3-2 win at Nottingham Forest last weekend and was seen after the match using his shirt to put his arm in a temporary sling.
Newcastle were initially hopeful that Wilson had not sustained a serious injury and that he could feature in some capacity against former club Bournemouth at St James' Park on Saturday.
Speaking to reporters after the win at Forest, manager Eddie Howe said: «It's a slight concern for us after the game. His shoulder is fine but he looks like there is a problem with one of the muscles in his arm. We're hopeful it is not serious but at this moment we don't know.»
However, according to the Daily Mail, Wilson is set to undergo a pectoral tendon operation this week which could rule him out until early May, sidelining the striker for the majority of the campaign.
Wilson will also miss England's international friendlies against Brazil and Belgium in March and is facing a race against time to be fit for Euro 2024 this summer.
The report adds that the best-case scenario for Wilson is a return at some stage in April – the Magpies have eight Premier League fixtures in April followed by three more in May.
Newcastle's No.9 has been hampered with several injury setbacks throughout his career and has already missed 13 competitive matches in all competitions this season with hamstring and calf problems.
Wilson was sidelined for five matches in January with a calf injury before making his first appearance of 2024 as a half-time substitute in Newcastle's 4-4 draw with Luton Town a fortnight ago.
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