Luis Diaz missed a penalty for Colombia on a difficult night but there was cause for celebration for Liverpool pair Darwin Nunez and Dominik Szoboszlai.
The Merseyside derby is just 72 hours away and for Jurgen Klopp, time will be minimal to prepare for one of the most anticipated matches in the football calendar.
After the previous international break in September, by the time of the German's press conference for their trip to Wolves, he was awaiting the return of some of the South American contingent.
The Reds boss now faces a wait to see what condition his stars return in - but this time around it should be slightly easier for those featuring in the COMNEBOL World Cup qualification group.
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Alexis Mac Allister looked jaded at Molineux after the short turnaround from his outing against Bolivia and is set for a slightly longer recovery period, albeit a day or so more. The 24-year-old featured for Argentina as Lionel Messi took centre stage against Peru.
The Inter Miami star scored two goals in 10 minutes before the break to extend their lead at the top of the group, with their quest to defend their crown ongoing.
They face pressure from nearest challengers Uruguay who made home advantage count against Brazil. Alisson Becker's time on the bench continued after Fernando Diniz opted in favour of Ederson.
Whether the decision backfired is up for discussion but it was a superb night for Liverpool striker Darwin Nunez. The 24-year-old scored his fourth goal for Uruguay, opening the scoring with a diving header, before assisting the second in their 2-0 win over
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