The former Bayern Munich man started Sunday's EFL Cup final with Chelsea at Wembley but was forced off in the first half, having been the victim of a crunching tackle from Moises Caicedo.
Klopp confirmed immediately after the Reds' 1-0 extra-time success that Gravenberch had not suffered any fractures, but the Dutchman — who was stretchered off the field — had sustained ligament damage.
The Liverpool boss unsurprisingly did not put a timeframe on Gravenberch's recuperation over the weekend, but the 21-year-old was never expected to make a miraculous recovery in time for the visit of the Saints.
Speaking to reporters in Tuesday's pre-game press conference, Klopp announced that Gravenberch would not be fit to face Russell Martin's side, but he did not rule the midfielder out of the weekend's Premier League clash with Nottingham Forest.
«What I know is that Ryan is not available, besides all the others who are not available,» Klopp said. «It's a ligament injury, could have been much worse, but bad enough for being ruled out for this game. Next game, we will see. So, we need miracles with a few players, so that's why I don't want to rule out for too long.»
Gravenberch will be one of nine definite absentees for a decimated Liverpool side on Wednesday, where Thiago Alcantara (muscle), Stefan Bajcetic (calf), Ben Doak (knee), Joel Matip (knee), Curtis Jones (shin), Alisson Becker (hamstring), Diogo Jota (knee) and Trent Alexander-Arnold (knee) will also be unavailable.
The ex-Ajax protege was one of two Liverpool lynchpins to come off worse for wear at
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