As the Premier League returns with a Saturday packed full of huge matches, talkSPORT gets the action started at Anfield.
But that's not all there is, with a Rugby World Cup semi-final, a London derby and a packed UFC card among the other offerings.
Here, talkSPORT runs through what is an epic day of sport.
Liverpool are sitting in a comfortable fourth place in the Premier League table having picked up five wins out of their opening eight games.
The bad news for Jurgen Klopp is that the Reds lost to Tottenham and only managed a draw with Brighton just before the international break.
And Klopp has a new worry: the Reds are without Andy Robertson after the left-back suffered a shoulder injury while on international duty with Scotland.
His absence could open up a gap in their defence for Everton to exploit.
The Toffees were winless in their first five games, but have since picked up two much-needed wins.
But Everton are up against the odds, having won just one out of the last 25 previous Merseyside derbies.
Liverpool vs Everton is live on talkSPORT at 12:30pm on October 21
The Magpies have been on an impressive run of form across all competitions, knocking last year's treble winners Manchester City out the Carabao Cup while defeating Paris Saint-Germain 4-1 in the Champions League.
But Crystal Palace proved to be an unbeatable obstacle for Newcastle last season.
They recorded a goalless draw against Palace in all three of their meetings last season in all competitions.
Newcastle are without Joe Willock and Harvey Barnes through injury — but Sandro Tonali is available, despite allegations of illegal betting which led to him being sent home from Italy's national team squad.
Meanwhile, Palace have been defensively impressive this
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